Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.71 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.71 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.71 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7371901 | 0.99 | HRH3 (0.79) | HRH3MEN1KMT2AHRH4KDM4E | |
| SCHEMBL11093348 | 0.89 | HRH3 (1.00) | HRH3MEN1KMT2A | |
| SCHEMBL7369141 | 0.88 | HRH4 (0.97) | HRH3HRH4KDM4EALDH1A1PSMB1 | |
| SCHEMBL491769 | 0.88 | HRH3 (0.97) | HRH3MEN1KMT2A | |
| SCHEMBL7373952 | 0.87 | HRH3 (0.80) | HRH3MEN1KMT2AHRH4KDM4E | |
| Hydrochloric Acid SCHEMBL7407264 | 0.87 | HRH4 (0.95) | HRH3HRH4KDM4EALDH1A1PSMB1 | |
| SCHEMBL9360133 | 0.87 | HRH4 (1.00) | HRH3HRH4KDM4EALDH1A1PSMB1 | |
| SCHEMBL491674 | 0.87 | HRH4 (1.00) | HRH3HRH4KDM4EALDH1A1PSMB1 | |
| SCHEMBL4746238 | 0.86 | HRH3 (0.65) | HRH3MEN1KMT2AHRH4KDM4E | |
| SCHEMBL4743140 | 0.86 | HRH3 (0.65) | HRH3MEN1KMT2AHRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724577-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | claimed |
| WO-1995011238-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | claimed |
| EP-0724577-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011238-A1 | HETEROCYCLIC AMINES FOR TREATING ISCHAEMIC STROKES | SMITHKLINE BEECHAM PLC (GB) | 1995-04-27 | — | — | WO | disclosed |