Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775649 | 0.94 | MEN1 (0.67) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL21775559 | 0.94 | MEN1 (0.67) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL20553331 | 0.94 | MEN1 (0.67) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL8825150 | 0.88 | MEN1 (0.70) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL7367538 | 0.87 | MEN1 (0.62) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL9014015 | 0.87 | MEN1 (0.62) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL7364771 | 0.87 | MEN1 (0.62) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL11449949 | 0.86 | MEN1 (0.68) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL23612629 | 0.86 | MEN1 (0.60) | MEN1KMT2AOPRM1OPRD1LMNA | |
| SCHEMBL7367855 | 0.85 | MEN1 (0.63) | MEN1KMT2AOPRM1OPRD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994002463-A1 | ANTIHYPERTENSIVE 1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-03 | — | — | WO | disclosed |