Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR1E | P28566 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28426480 | 0.89 | HTT (0.52) | RAB9ASMN1; SMN2NPC1TMEM97SIGMAR1 | |
| SCHEMBL7007408 | 0.89 | TMEM97 (0.56) | RAB9ASMN1; SMN2NPC1L3MBTL1TMEM97 | |
| SCHEMBL8386105 | 0.87 | KMT2A (0.52) | RAB9ASMN1; SMN2NPC1TMEM97SIGMAR1 | |
| SCHEMBL4388657 | 0.86 | MEN1 (0.45) | RAB9ASMN1; SMN2NPC1TMEM97SIGMAR1 | |
| SCHEMBL28432287 | 0.86 | MEN1 (0.47) | RAB9ASMN1; SMN2NPC1L3MBTL1TMEM97 | |
| SCHEMBL16475199 | 0.84 | TMEM97 (0.52) | RAB9ASMN1; SMN2NPC1TMEM97SIGMAR1 | |
| SCHEMBL3902852 | 0.83 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2NPC1L3MBTL1TMEM97 | |
| SCHEMBL28429226 | 0.82 | MEN1 (0.48) | RAB9ASMN1; SMN2NPC1TMEM97SIGMAR1 | |
| SCHEMBL28439343 | 0.82 | MEN1 (0.50) | RAB9ASMN1; SMN2NPC1L3MBTL1TMEM97 | |
| SCHEMBL5551353 | 0.82 | KDM4E (0.62) | RAB9ASMN1; SMN2NPC1L3MBTL1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211183-B1 | PIPERAZINE DERIVATIVE ANTICOAGULANTS; ANTIISCHEMIC AGENTS; CARDIOVASCULAR DISORDERS | COR THERAPEUTICS, INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0975625-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998046591-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |