Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.64 |
| ▸ | PDE4A | P27815 | 4/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29682915 | 0.96 | PDE4B (0.69) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23499796 | 0.96 | PDE4B (0.69) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL8890462 | 0.86 | PDE4B (0.71) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084849 | 0.86 | PDE4D (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2889923 | 0.86 | PDE4D (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL8889614 | 0.85 | PDE4D (0.73) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL14705239 | 0.84 | PDE4B (0.65) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2887354 | 0.84 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084843 | 0.84 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084827 | 0.83 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706513-B1 | FLUOROALKOXY-SUBSTITUTED BENZAMIDES AND THEIR USE AS CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS | BYK GULDEN LOMBERG CHEM FAB (DE) | 2002-05-15 | — | — | EP | disclosed |
| EP-0706513-A1 | FLUOROALKOXY-SUBSTITUTED BENZAMIDES AND THEIR USE AS CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001338-A1 | FLUOROALKOXY-SUBSTITUTED BENZAMIDES AND THEIR USE AS CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1995-01-12 | — | — | WO | disclosed |