⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2043770 | 0.79 | — | — | |
| SCHEMBL2271987 | 0.65 | — | — | |
| SCHEMBL2279468 | 0.65 | — | — | |
| SCHEMBL337298 | 0.64 | — | — | |
| SCHEMBL107513 | 0.62 | — | — | |
| SCHEMBL23483170 | 0.61 | — | — | |
| SCHEMBL762605 | 0.61 | — | — | |
| SCHEMBL526328 | 0.61 | — | — | |
| SCHEMBL3424136 | 0.61 | — | — | |
| SCHEMBL6699136 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665724-A1 | TYPE II TOPOISOMERASE INHIBITORS AND METHODS OF MAKING AND USING THEREOF | Ohio State Innovation Foundation (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173781-A1 | TYPE II TOPOISOMERASE INHIBITORS AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2024-08-22 | — | — | WO | disclosed |
| EP-3612513-A1 | TYPE II TOPOISOMERASE INHIBITORS AND METHODS OF MAKING AND USING THEREOF | Ohio State Innovation Foundation (US) | 2020-02-26 | — | — | EP | disclosed |
| WO-2018195098-A1 | TYPE II TOPOISOMERASE INHIBITORS AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2018-10-25 | — | — | WO | disclosed |
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |
| CN-1189830-A | Substituted 1, 3-dioxan-5-ylamino-heterocyclic compounds, method for the production thereof and use thereof as pest control agents | HOECHST SCHERING AGREVO GMBH (DE) | 1998-08-05 | — | — | CN | disclosed |
| CN-1189830-A | Substituted 1, 3-dioxan-5-ylamino-heterocyclic compounds, method for the production thereof and use thereof as pest control agents | HOECHST SCHERING AGREVO GMBH (DE) | 1998-08-05 | — | — | CN | disclosed |
| EP-0836603-A1 | SUBSTITUTED 1,3-DIOXAN-5-YLAMINO HETEROCYCLIC COMPOUNDS, METHODS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002264-A1 | SUBSTITUTED 1,3-DIOXAN-5-YLAMINO HETEROCYCLIC COMPOUNDS, METHODS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-23 | — | — | WO | disclosed |
| EP-0576605-A4 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | RAJADHYAKSHA VITHAL J (US) | 1994-06-08 | — | — | EP | disclosed |
| WO-1994010161-A1 | 1,3-DIOXANE DERIVATIVES HAVING PROTEIN KINASE C INHIBITORY ACTIVITY | SPHINX PHARMACEUTICALS CORPORATION (US) | 1994-05-11 | — | — | WO | disclosed |
| EP-0576605-A1 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | THERAPEUTIC PATCH RESEARCH N.V. (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016236-A1 | COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS | RAJADHYAKSHA VITHAL J (US) | 1992-10-01 | — | — | WO | disclosed |