Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4713972 | 0.77 | CHKA (0.53) | CHKAITGB3ITGA2BADRB2NCF1 | |
| SCHEMBL6168131 | 0.77 | F10 (0.48) | CHKAF10ITGB3ITGA2BLSS | |
| SCHEMBL6168128 | 0.77 | F10 (0.46) | CHKAF10ITGB3ITGA2BLSS | |
| SCHEMBL6895764 | 0.77 | CYP2C19 (0.46) | CHKAF10ITGB3ITGA2BADRB2 | |
| SCHEMBL4714567 | 0.74 | CHKA (0.50) | CHKAF10ITGB3ITGA2BADRB2 | |
| SCHEMBL4712975 | 0.74 | CHKA (0.50) | CHKAITGB3ITGA2BADRB2NCF1 | |
| SCHEMBL785122 | 0.74 | CHKA (0.53) | CHKAF10ADRB2NCF1PLD1 | |
| SCHEMBL4717561 | 0.74 | CHKA (0.53) | CHKAF10ITGB3ITGA2BADRB2 | |
| SCHEMBL5760023 | 0.74 | CHKA (0.53) | CHKAF10ITGB3ITGA2BADRB2 | |
| SCHEMBL1648623 | 0.74 | CHKA (0.53) | CHKAF10ITGB3ITGA2BADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999000128-A9 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 1999-08-05 | — | — | WO | disclosed |