Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367021 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTKMT2ACYP1A2CYP3A4 | |
| SCHEMBL6946424 | 0.92 | MAPT (0.48) | SMN1; SMN2MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL6946420 | 0.92 | MAPT (0.48) | SMN1; SMN2MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL6941319 | 0.89 | PDE5A (0.52) | SMN1; SMN2MAPTKMT2AMEN1PDE5A | |
| SCHEMBL6944497 | 0.89 | PDE5A (0.52) | SMN1; SMN2MAPTKMT2AMEN1PDE5A | |
| SCHEMBL6941322 | 0.89 | PDE5A (0.52) | SMN1; SMN2MAPTKMT2AMEN1PDE5A | |
| SCHEMBL6941929 | 0.86 | MAPT (0.45) | SMN1; SMN2MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL6941936 | 0.86 | MAPT (0.45) | SMN1; SMN2MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL6940780 | 0.85 | NPSR1 (0.43) | SMN1; SMN2MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL6940784 | 0.85 | NPSR1 (0.43) | SMN1; SMN2MAPTKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |