Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL7377125 | 0.87 | ACE (0.52) | ACEMME | |
| Benzene SCHEMBL7366164 | 0.86 | ACE (0.51) | ACEMME | |
| Benzene SCHEMBL10567370 | 0.86 | ACE (0.51) | ACEMME | |
| Benzene SCHEMBL10566919 | 0.84 | ACE (0.50) | ACEMME | |
| Benzene SCHEMBL7370830 | 0.83 | ACE (0.49) | ACEMME | |
| Benzene SCHEMBL10567835 | 0.80 | ACE (0.39) | ACE | |
| SCHEMBL10568535 | 0.72 | MME (0.43) | ACEMME | |
| SCHEMBL8310023 | 0.66 | MME (0.59) | ACEMME | |
| Benzene SCHEMBL10806387 | 0.66 | MME (0.51) | ACEMME | |
| SCHEMBL31367029 | 0.66 | MME (0.49) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280627-B1 | DERIVATIVES OF N-SUBSTITUTED ALPHA-MERCAPTOMETHYL-BENZENE-PROPANAMIDE, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-04-21 | — | — | EP | disclosed |
| US-4839358-A | ANALGESICS, ANTIDEPRESSANTS, ANTIANXIETY AGENTS | ROUSSEL UCLAF (FR) | 1989-06-13 | — | — | US | disclosed |
| EP-0280627-A2 | Derivatives of N-substituted alpha-mercaptomethyl-benzene-propanamide, process for their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1988-08-31 | — | — | EP | disclosed |