Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | SLC9A3 | P48764 | 8/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7375932 | 0.99 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| SCHEMBL7370489 | 0.94 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7370002 | 0.93 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL8636790 | 0.93 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7369999 | 0.93 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| SCHEMBL7375364 | 0.91 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7368016 | 0.89 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| SCHEMBL7372156 | 0.89 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7367973 | 0.87 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 | |
| SCHEMBL7374725 | 0.86 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3SLC9A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711272-A1 | INDANE AND TETRAHYDRONAPHTHALENE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | claimed |
| WO-1995004028-A1 | INDANE AND TETRAHYDRONAPHTHALENE DERIVATIVES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | claimed |
| US-5773463-A | DECALCIFICATION OF BRAIN DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-06-30 | — | — | US | disclosed |