Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7373331 | 0.78 | KMT2A (0.57) | MAPTRAB9AMAOBKMT2ALMNA | |
| SCHEMBL7367540 | 0.77 | CYP3A4 (0.55) | MAPTRAB9AMAOBKMT2ALMNA | |
| SCHEMBL30584138 | 0.77 | HTT (0.66) | MAPTRAB9AMAOBLMNANPC1 | |
| SCHEMBL6142808 | 0.76 | KMT2A (0.46) | KMT2ALMNACYP1A2CYP2D6CYP3A4 | |
| SCHEMBL7398206 | 0.75 | KMT2A (0.42) | RAB9AKMT2ALMNANPC1MEN1 | |
| SCHEMBL7398203 | 0.75 | KMT2A (0.42) | RAB9AKMT2ALMNANPC1MEN1 | |
| SCHEMBL10932498 | 0.73 | CYP3A4 (0.56) | MAPTRAB9AMAOBKMT2ALMNA | |
| SCHEMBL8155004 | 0.72 | TNFRSF1A (0.71) | MAPTRAB9AMAOBKMT2ALMNA | |
| SCHEMBL7194844 | 0.72 | TNFRSF1A (0.71) | MAPTRAB9AMAOBKMT2ALMNA | |
| SCHEMBL8155008 | 0.72 | TNFRSF1A (0.71) | MAPTRAB9AMAOBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822805-A | ANTIINFLAMMATORY AGENTS, CARDIOTONIC AGENTS, ANTIPLATELET AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257897-A1 | Imidazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |