Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 13/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 10/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369862 | 1.00 | FFAR1 (0.51) | FFAR1PPARAPARP15PARP10FFAR4 | |
| SCHEMBL7371960 | 0.89 | FFAR1 (0.50) | FFAR1PPARAPARP15PARP10FFAR4 | |
| SCHEMBL7378367 | 0.88 | FFAR1 (0.48) | FFAR1PPARAPARP15PARP10FFAR4 | |
| SCHEMBL1345209 | 0.87 | MAOB (0.50) | PPARAMAOBMAOA | |
| SCHEMBL7377110 | 0.87 | MAOB (0.50) | MAOBMAOA | |
| SCHEMBL1346559 | 0.87 | MAOB (0.50) | MAOBMAOA | |
| SCHEMBL1346598 | 0.87 | MAOB (0.50) | PPARAMAOBMAOA | |
| SCHEMBL1347012 | 0.86 | KDM1A (0.52) | KDM1A | |
| SCHEMBL1346720 | 0.86 | MAOB (0.51) | MAOBMAOA | |
| SCHEMBL1347064 | 0.85 | PPARA (0.42) | FFAR1PPARAFFAR4MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842152-B1 | N-(4-SUBSTITUTED-BENZYL)-2-AMINOLACTAM DERIVATIVES | NEWRON PHARM SPA (IT) | 2001-01-31 | — | — | EP | disclosed |
| EP-0842152-A1 | N-(4-SUBSTITUTED-BENZYL)-2-AMINOLACTAM DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005111-A1 | N-(4-SUBSTITUTED-BENZYL)-2-AMINOLACTAM DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-02-13 | — | — | WO | disclosed |