Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374872 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL10527890 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| Hydrochloric Acid SCHEMBL7399417 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL10527161 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL7370226 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL7371737 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL10525007 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL7371620 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL7370753 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B | |
| SCHEMBL7369584 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP2C19NPC1RAB9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882326-A | HYPOTENSIVE AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0292923-A2 | Piperidine compounds and pharmaceutical uses thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-11-30 | — | — | EP | disclosed |