Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19883747 | 0.85 | CA14 (0.40) | ALDH1A1LMNACA14L3MBTL1HDAC6 | |
| SCHEMBL7016953 | 0.82 | CA14 (0.46) | CA14HDAC6CA12CA2HDAC1 | |
| SCHEMBL1121023 | 0.82 | CA14 (0.36) | ALDH1A1LMNACA14L3MBTL1HDAC6 | |
| SCHEMBL4686524 | 0.82 | CA14 (0.42) | ALDH1A1LMNACA14L3MBTL1HDAC6 | |
| SCHEMBL3838042 | 0.81 | CA14 (0.44) | CA14HDAC6CA12CA2HDAC1 | |
| SCHEMBL24111622 | 0.80 | CA14 (0.51) | ALDH1A1LMNACA14L3MBTL1HDAC6 | |
| SCHEMBL2306068 | 0.80 | CA14 (0.42) | ALDH1A1LMNACA14L3MBTL1HDAC6 | |
| SCHEMBL19032434 | 0.79 | CA14 (0.47) | LMNACA14HDAC6CA12CA2 | |
| SCHEMBL20561267 | 0.79 | CA14 (0.47) | LMNACA14HDAC6CA12CA2 | |
| SCHEMBL7368645 | 0.79 | TSHR (0.44) | ALDH1A1CA14HDAC6CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539104-A | 1,4 Diazocines as fibrinogen antagonists | SMITHKLINE BEECHAM CORP. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0610432-A1 | C8-CYCLIC PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009133-A1 | C8-CYCLIC PEPTIDOMIMETICS AS FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-05-13 | — | — | WO | disclosed |