Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25927732 | 0.89 | PPIB (0.56) | PPIBCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL1502008 | 0.86 | PPIB (0.52) | PPIBCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31070317 | 0.86 | PPIB (0.52) | PPIBCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15338789 | 0.86 | PPIB (0.52) | PPIBCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL1818976 | 0.86 | PPIB (0.52) | PPIBCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1820365 | 0.86 | PPIB (0.52) | PPIBCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL25274050 | 0.85 | PPIB (0.57) | PPIBCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL25274049 | 0.85 | PPIB (0.57) | PPIBCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL29396441 | 0.85 | PPIB (0.57) | PPIBCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL25223531 | 0.84 | PPIB (0.58) | PPIBCYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243959-B1 | SUBSTITUTED BENZAMIDE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-4870074-A | Substituted benzamide derivatives, for enhancing gastrointestinal motility | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0243959-A1 | Substituted benzamide derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-04 | — | — | EP | disclosed |