Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 6/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994583 | 0.93 | MEN1 (0.53) | MEN1GAAKMT2AGFPT1MAOA | |
| SCHEMBL994584 | 0.93 | MEN1 (0.53) | MEN1GAAKMT2AGFPT1MAOA | |
| SCHEMBL997508 | 0.93 | MEN1 (0.53) | MEN1GAAKMT2AGFPT1MAOA | |
| Hydrochloric Acid SCHEMBL2680968 | 0.92 | MEN1 (0.51) | MEN1GAAKMT2AGFPT1MAOA | |
| Hydrochloric Acid SCHEMBL668972 | 0.92 | MEN1 (0.51) | MEN1GAAKMT2AGFPT1MAOA | |
| Hydrochloric Acid SCHEMBL2681229 | 0.92 | MEN1 (0.51) | MEN1GAAKMT2AGFPT1MAOA | |
| Chloromethane SCHEMBL17911911 | 0.92 | MEN1 (0.51) | MEN1GAAKMT2AGFPT1MAOA | |
| SCHEMBL23455458 | 0.83 | MEN1 (0.46) | MEN1GAAKMT2AGFPT1MAOA | |
| SCHEMBL23455605 | 0.83 | MEN1 (0.46) | MEN1GAAKMT2AGFPT1MAOA | |
| SCHEMBL13365413 | 0.81 | MEN1 (0.47) | MEN1GAAKMT2AGFPT1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049693-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS $g(a) v?$g(b) 3? ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999026945-A1 | 1,3,4-THIADIAZOLES AND 1,3,4-OXADIAZOLES AS αvβ3 ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |