Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7366575 | 0.94 | F2 (0.76) | F2PRSS1 | |
| SCHEMBL7361823 | 0.89 | F2 (0.83) | F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7365223 | 0.85 | F2 (0.76) | F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7369968 | 0.85 | F2 (0.81) | F2PRSS1 | |
| SCHEMBL7371116 | 0.85 | F2 (1.00) | F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7369104 | 0.85 | F2 (0.80) | F2PRSS1 | |
| SCHEMBL7715240 | 0.84 | F2 (1.00) | F2 | |
| Trifluoroacetic Acid SCHEMBL7408458 | 0.84 | F2 (0.76) | F2PRSS1 | |
| SCHEMBL7368175 | 0.84 | F2 (1.00) | F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7369573 | 0.83 | F2 (0.79) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259506-A1 | PYRAZINONE THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| US-6387911-B1 | Pyrazinone thrombin inhibitors | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |
| WO-2001038323-A1 | PYRAZINONE THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2001-05-31 | — | — | WO | disclosed |