Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16884075 | 0.88 | KDM4E (0.67) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL5784912 | 0.86 | HTT (0.55) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL7411268 | 0.82 | MEN1 (0.57) | ALDH1A1MEN1KMT2APOLBCYP2C9 | |
| SCHEMBL10899727 | 0.81 | GAA (0.71) | KDM4EALDH1A1TDP1HTTPOLB | |
| SCHEMBL21957070 | 0.78 | HTT (0.67) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL15330913 | 0.77 | HTT (0.62) | ALDH1A1KMT2AHTTSMN1; SMN2TSHR | |
| SCHEMBL16883438 | 0.75 | HTT (0.56) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL10334149 | 0.75 | KDM4E (0.75) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL16884088 | 0.75 | HTT (0.76) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL7413309 | 0.75 | GAA (0.55) | KDM4EALDH1A1HTTPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049662-A1 | INHIBITORS OF ALPHA4 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999036393-A1 | INHIBITORS OF α4 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 1999-07-22 | — | — | WO | disclosed |