Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.65 |
| ▸ | PDE4A | P27815 | 10/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370957 | 1.00 | PDE4B (0.65) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7367082 | 0.91 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7367087 | 0.91 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7369258 | 0.87 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7369262 | 0.87 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7439087 | 0.86 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7439091 | 0.86 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7439083 | 0.86 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7367517 | 0.83 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7373715 | 0.83 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027947-A1 | PHENYLCYCLOPROPANE COMPOUNDS AND THEIR USE AS cAMP AND TNF INHIBITORS | RHONE-POULENC RORER LTD. (GB) | 1994-12-08 | — | — | WO | claimed |
| WO-1994027947-A1 | PHENYLCYCLOPROPANE COMPOUNDS AND THEIR USE AS cAMP AND TNF INHIBITORS | RHONE-POULENC RORER LTD. (GB) | 1994-12-08 | — | — | WO | disclosed |