Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377093 | 0.98 | AVPR2 (0.43) | MTTPAVPR2AVPR1AAVPR1BTP53 | |
| SCHEMBL7376477 | 0.96 | MTTP (0.42) | MTTPALDH1A1HPGDAVPR2AVPR1A | |
| SCHEMBL7379146 | 0.95 | MTTP (0.44) | MTTPALDH1A1HPGDAVPR2AVPR1A | |
| SCHEMBL7519200 | 0.95 | MTTP (0.42) | MTTPALDH1A1HPGDAVPR2AVPR1A | |
| SCHEMBL8812490 | 0.93 | TP53 (0.41) | MTTPALDH1A1HPGDAVPR2AVPR1A | |
| SCHEMBL7371222 | 0.93 | MAPT (0.45) | MTTPALDH1A1AVPR2MAPTHTT | |
| SCHEMBL7377966 | 0.93 | MTTP (0.41) | MTTPALDH1A1HPGDAVPR2AVPR1A | |
| SCHEMBL7370349 | 0.92 | GAA (0.41) | MTTPALDH1A1AVPR2AVPR1AAVPR1B | |
| SCHEMBL7371186 | 0.91 | AVPR2 (0.42) | MTTPALDH1A1AVPR2AVPR1AAVPR1B | |
| SCHEMBL7335216 | 0.90 | MEN1 (0.46) | TP53GAAHSP90AA1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |