Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.71 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.51 |
| ▸ | WNT3A | P56704 | 2/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17232878 | 0.87 | PBRM1 (0.71) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| SCHEMBL11981364 | 0.83 | PBRM1 (0.67) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| SCHEMBL50742 | 0.83 | PBRM1 (1.00) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| SCHEMBL27320955 | 0.83 | PBRM1 (0.67) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| SCHEMBL29531272 | 0.83 | PBRM1 (1.00) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| SCHEMBL6160620 | 0.83 | PBRM1 (0.67) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| SCHEMBL13134166 | 0.83 | PBRM1 (0.67) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| SCHEMBL12441827 | 0.83 | PBRM1 (0.67) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| SCHEMBL21246198 | 0.83 | PBRM1 (0.67) | PBRM1GPR84ALDH1A1ATMNR4A2 | |
| Hydrochloric Acid SCHEMBL9481167 | 0.82 | PBRM1 (0.96) | PBRM1GPR84ALDH1A1ATMNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722436-A4 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | UNIV FLORIDA STATE (US) | 1996-11-20 | — | — | EP | disclosed |
| EP-0722436-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009833-A1 | MERCAPTOSULFIDE METALLOPROTEINASE INHIBITORS | FLORIDA STATE UNIVERSITY (US) | 1995-04-13 | — | — | WO | disclosed |
| US-4148908-A | BRONCHODILATORS | MEAD JOHNSON & COMPANY (US) | 1979-04-10 | — | — | US | disclosed |
| US-4055658-A | BETA-ADRENERGIC STIMULANTS, BRONCHIAL | MEAD JOHNSON & COMPANY (US) | 1977-10-25 | — | — | US | disclosed |