Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963981 | 0.87 | KDM4E (0.36) | KDM4EALDH1A1LMNAHTTTP53 | |
| SCHEMBL3222485 | 0.77 | DHODH (0.40) | KDM4EALDH1A1EGFR | |
| SCHEMBL2963896 | 0.75 | HSP90AB1 (0.35) | ALDH1A1NPC1RAB9ATP53EGFR | |
| SCHEMBL3460245 | 0.73 | DHODH (0.41) | KDM4EALDH1A1HTTPOLBMAPT | |
| SCHEMBL2968749 | 0.71 | CRACR2A (0.40) | KDM4ENPC1RAB9ATP53MAP4K4 | |
| SCHEMBL3459213 | 0.71 | KDM5A (0.38) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13266060 | 0.71 | PARP1 (0.33) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL13326891 | 0.70 | TSHR (0.46) | KDM4EALDH1A1GAAHPGDNPSR1 | |
| SCHEMBL13266037 | 0.69 | MIF (0.35) | ALDH1A1MEN1KMT2ANPSR1MIF | |
| SCHEMBL7381477 | 0.68 | NPC1 (0.48) | KDM4EALDH1A1LMNAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368343-B1 | AMELIORATING COMPOSITION FOR DYSMNESIA | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4990516-A | Pyrazolo (1,5-a)pyridine derivatives | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0368343-A2 | Ameliorating composition for dysmnesia | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1990-05-16 | — | — | EP | disclosed |