⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11685202 | 0.97 | — | — | |
| SCHEMBL17224702 | 0.87 | — | — | |
| SCHEMBL4747699 | 0.64 | — | — | |
| SCHEMBL3540492 | 0.58 | — | — | |
| SCHEMBL28198320 | 0.56 | — | — | |
| SCHEMBL660984 | 0.54 | — | — | |
| SCHEMBL11103590 | 0.54 | — | — | |
| SCHEMBL13227939 | 0.54 | — | — | |
| SCHEMBL7558516 | 0.54 | — | — | |
| SCHEMBL1073021 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248092-B | Functionalized polymers and tires improved therefrom | BRIDGESTONE CORP | 2012-12-05 | — | — | CN | claimed |
| CN-101248092-A | Functionalized polymers and tires improved therefrom | BRIDGESTONE CORP (JP) | 2008-08-20 | — | — | CN | claimed |
| CN-101084235-A | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS INC (US) | 2007-12-05 | — | — | CN | claimed |
| CN-1990477-A | Linear dicationic terphenyls and their aza analogues as antiparasitic agents | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2007-07-04 | — | — | CN | claimed |
| EP-3950673-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | Inspirna, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-3137447-B1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | RGENIX INC (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10717704-B2 | Inhibitors of creatine transport and uses thereof | RGENIX, INC. (US) | 2020-07-21 | — | — | US | disclosed |
| US-20190315680-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | INSPIRNA, INC. | 2019-10-17 | — | — | US | disclosed |
| US-10308597-B2 | Inhibitors of creatine transport and uses thereof | RGENIX, INC. (US) | 2019-06-04 | — | — | US | disclosed |
| EP-3137447-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | Rgenix, Inc. (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20170050924-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | INSPIRNA, INC. | 2017-02-23 | — | — | US | disclosed |
| WO-2016176636-A1 | INHIBITORS OF CREATINE TRANSPORT AND USES THEREOF | RGENIX, INC. (US) | 2016-11-03 | — | — | WO | disclosed |
| CN-1090178-C | Tricyclic compounds having activity specific for integrins, in particular alpha v beta 3 integrins, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 2002-09-04 | — | — | CN | disclosed |
| CN-1305492-A | Pyrazinone protease inhibitors | DIMENSIONAL PHARM INC (US) | 2001-07-25 | — | — | CN | disclosed |
| CN-1303365-A | Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors | DIMENSIONAL PHARM INC (US) | 2001-07-11 | — | — | CN | disclosed |
| CN-1284084-A | Echinocandin derivatives, their preparation and their use as antifungal agents | HOECHST MARION ROUSSEL INC (FR) | 2001-02-14 | — | — | CN | disclosed |
| CN-1237961-A | Aminoguanidines and alkoxyguanidines as protease inhibitors | DIMENSIONAL PHARM INC (US) | 1999-12-08 | — | — | CN | disclosed |
| CN-1219165-A | Tricyclic compounds having activity specific for integrins, in particular alpha v beta 3 integrins, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL CO (FR) | 1999-06-09 | — | — | CN | disclosed |
| WO-1996026190-A1 | INTEGRIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-29 | — | — | WO | disclosed |
| CN-1050023-A | The method for preparing cephalosporin derivative | BEECHAM GROUP PLC (GB) | 1991-03-20 | — | — | CN | disclosed |