Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 10/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.47 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374907 | 1.00 | KDM4E (0.49) | KDM4EALDH1A1POLBAVPR2AVPR1A | |
| SCHEMBL7377133 | 1.00 | KDM4E (0.49) | KDM4EALDH1A1POLBAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7749380 | 0.99 | KDM4E (0.48) | KDM4EALDH1A1POLBAVPR2AVPR1A | |
| SCHEMBL7376990 | 0.99 | KDM4E (0.49) | KDM4EALDH1A1POLBAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7376857 | 0.98 | KDM4E (0.49) | KDM4EALDH1A1POLBAVPR2AVPR1A | |
| SCHEMBL7377877 | 0.97 | AVPR2 (0.49) | KDM4EALDH1A1POLBAVPR2AVPR1A | |
| SCHEMBL7372942 | 0.90 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7751053 | 0.90 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7372097 | 0.89 | AVPR2 (0.46) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7375946 | 0.89 | NPSR1 (0.42) | ALDH1A1AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |