SCHEMBL7375014

SCHEMBL7375014

C=CCC(CC(N)=O)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.44
GRIK2 Q13002 2/20 0.44
CPA1 P15085 1/20 0.38
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
FGFR4 P22455 1/20 0.32
CYP2C19 P33261 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL174976 0.85 GRIK1 (0.50) GRIK1GRIK2CPA1ALDH1A1TSHR
SCHEMBL10435758 0.84 GRIK1 (0.57) GRIK1GRIK2CPA1ALDH1A1TSHR
SCHEMBL10479816 0.84 GRIK1 (0.47) GRIK1GRIK2CPA1TSHRCYP2C19
SCHEMBL23040815 0.83 GRIK1 (0.41) GRIK1GRIK2CPA1ALDH1A1TSHR
SCHEMBL26088512 0.81 GRIK1 (0.47) GRIK1GRIK2CPA1ALDH1A1TSHR
SCHEMBL28751205 0.79 GRIK1 (0.39) GRIK1GRIK2CPA1CA1CA2
SCHEMBL11869712 0.77
SCHEMBL9603288 0.77
SCHEMBL27804094 0.77 CA1 (0.30) CA1CA2
SCHEMBL293079 0.77 CA1 (0.39) ALDH1A1CYP2C19CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1102752-A1 SUCCINOYLAMINO LACTAMS AS INHIBITORS OF A BETA PROTEIN PRODUCTION Du Pont Pharmaceuticals Company (US) 2001-05-30 EP claimed
WO-2000007995-A1 SUCCINOYLAMINO LACTAMS AS INHIBITORS OF Aβ PROTEIN PRODUCTION DU PONT PHARMACEUTICALS COMPANY (US) 2000-02-17 WO claimed
EP-0866817-B1 PROCESS FOR PREPARING SELF-RELEASING, COMPACT OR CELLULAR MOULDED BODIES OPTIONALLY CONTAINING REINFORCING AGENTS AND MADE OF POLYISOCYANATE POLYADDITON PRODUCTS AND INTERNAL MOULD RELEASE AGENTS THEREFOR BASF AG (DE) 1999-09-01 EP claimed
EP-0383359-A2 Process for preparing an overbased additive containing a boron derivative, additive produced by said process and lubricating compositions containing said additive ELF ANTAR FRANCE (FR) 1990-08-22 EP claimed
US-4859352-A BLEND OF LITHIUM SOAP, SYNTHETIC OIL, AND ADJUVANTS AMOCO CORPORATION (US) 1989-08-22 US claimed
JP-9078074-A None JP disclosed
CN-113631595-B Polymer composition and use thereof 罗地亚经营管理公司 2023-04-11 CN disclosed
CN-115698128-A Tocopherol-based nonionic and anionic surfactants 巴斯夫欧洲公司 2023-02-03 CN disclosed
CN-114981057-A Method for vulcanizing green tire using organopolysiloxane-based mold release lubricating composition 埃肯有机硅法国简易股份公司 2022-08-30 CN disclosed
CN-110225963-B Polyorganosiloxane-based composition intended for tyre moulding-demoulding 埃肯有机硅法国简易股份公司 2022-01-11 CN disclosed
CN-113874411-A Structure of associative polymers and method of use thereof 罗地亚经营管理公司 2021-12-31 CN disclosed
CN-110612336-B Method for producing a water-repellent and anti-adhesive coating on a support 埃肯有机硅法国简易股份公司 2021-11-09 CN disclosed
US-5965495-A BASE OIL; ASHLESS DISPERSANT CONTAINING BORON IN A SPECIFIC AMOUNT OR MORE RELATIVE TO THE TOTAL METAL CONTENT; METALLIC DETERGENT; OXIDATION STABILITY, LOW SULFATED ASH; RESISTANCE TO COKING; APPARATUS FOR EXHAUST GAS TREATMENT NOT AFFECTED IDEMITSU KOSAN CO., LTD. (JP) 1999-10-12 US disclosed
EP-0816477-A1 INTERNAL-COMBUSTION ENGINE OIL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-01-07 EP disclosed
US-5672570-A DECREASED ASH CONTENT; DETERGENCY IDEMITSU KOSAN CO., LTD. (JP) 1997-09-30 US disclosed
JP-H0978074-A LIGHT OIL COMPOSITION NIPPON OIL CO LTD 1997-03-25 JP disclosed
US-5525247-A CONTAINING BORON-CONTAINING DISPERSANT AND DETERGENT IDEMITSU KOSAN CO., LTD. (JP) 1996-06-11 US disclosed
EP-0383359-A2 Process for preparing an overbased additive containing a boron derivative, additive produced by said process and lubricating compositions containing said additive ELF ANTAR FRANCE (FR) 1990-08-22 EP disclosed
EP-0308445-A1 PROCESS FOR THE PREPARATION OF A SUPERALKALINIZED ADDITIVE CONTAINING AN INORGANIC BORON DERIVATIVE, ADDITIVE PRODUCED BY SAID PROCESS AND LUBRICATING COMPOSITIONS CONTAINING SAID ADDITIVE. ELF FRANCE (FR) 1989-03-29 EP disclosed
WO-1988007073-A1 PROCESS FOR THE PREPARATION OF A SUPERALKANIZED ADDITIVE CONTAINING A BORON DERIVATIVE, ADDITIVE PRODUCED BY SAID PROCESS AND LUBRICATING COMPOSITIONS CONTAINING SAID ADDITIVE ELF FRANCE (FR) 1988-09-22 WO disclosed