Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7375476

CC(=O)OC(C)(C)C.O=C(O)C(F)(F)F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
DGAT1 O75907 1/20 0.34
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL3021120 0.87 GAA (0.48) GAAALDH1A1TSHRDGAT1
Acetic Acid SCHEMBL25259384 0.84 GAA (0.46) GAAALDH1A1TSHRDGAT1
Acetic Acid SCHEMBL28991773 0.84 GAA (0.46) GAAALDH1A1TSHRDGAT1
Bicarbonate SCHEMBL28020933 0.84 GAA (0.46) GAAALDH1A1TSHRDGAT1
Acetic Acid SCHEMBL2928244 0.84 GAA (0.46) GAAALDH1A1TSHRDGAT1
SCHEMBL28342310 0.84 GAA (0.50) GAAALDH1A1TSHRDGAT1
SCHEMBL26684 0.84
SCHEMBL28745990 0.84 GAA (0.50) GAAALDH1A1TSHRDGAT1
SCHEMBL28358909 0.84 GAA (0.50) GAAALDH1A1TSHRDGAT1
SCHEMBL29804025 0.82 GAA (0.41) GAAALDH1A1TSHRDGAT1CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651224-A A kind of fluorescence protein crosslinking agent and preparation method thereof 苏州昊帆生物股份有限公司 2019-04-19 CN claimed
CN-109651224-A A kind of fluorescence protein crosslinking agent and preparation method thereof 苏州昊帆生物股份有限公司 2019-04-19 CN disclosed
CN-107428734-A Compounds and methods for targeted degradation of androgen receptors 阿尔维纳斯股份有限公司 2017-12-01 CN disclosed
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP disclosed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed