Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 20/20 | 0.64 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.52 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004182 | 0.87 | AVPR2 (0.65) | AVPR2AVPR1AOXTR | |
| SCHEMBL6992375 | 0.81 | AVPR2 (0.57) | AVPR2AVPR1AOXTR | |
| SCHEMBL7001058 | 0.81 | AVPR2 (0.78) | AVPR2AVPR1AOXTR | |
| SCHEMBL6997469 | 0.78 | AVPR2 (1.00) | AVPR2AVPR1A | |
| SCHEMBL7092064 | 0.77 | AVPR2 (0.69) | AVPR2AVPR1AOXTR | |
| SCHEMBL6997140 | 0.76 | AVPR2 (0.84) | AVPR2AVPR1A | |
| SCHEMBL7000720 | 0.75 | AVPR2 (1.00) | AVPR2AVPR1A | |
| SCHEMBL7002070 | 0.74 | AVPR2 (0.82) | AVPR2AVPR1A | |
| SCHEMBL7332051 | 0.73 | AVPR2 (0.72) | AVPR2AVPR1AOXTR | |
| SCHEMBL6993636 | 0.73 | AVPR2 (0.84) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021444-A1 | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-07-26 | — | — | EP | claimed |
| WO-1998020011-A1 | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-14 | — | — | WO | claimed |