Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356482 | 0.84 | TDP1 (0.59) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL8356396 | 0.84 | TDP1 (0.59) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL24418335 | 0.83 | TDP1 (0.58) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL18688676 | 0.83 | TDP1 (0.58) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL3222258 | 0.83 | TDP1 (0.58) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL500234 | 0.81 | TDP1 (0.55) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL8356253 | 0.81 | TDP1 (0.63) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL137629 | 0.78 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL136815 | 0.78 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL3025184 | 0.78 | TDP1 (0.85) | TDP1MAOAMAOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |