Sugi Predict

Sugi Predict / Compounds / SCHEMBL7375799

SCHEMBL7375799

SCHEMBL7375799

Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1ccc(C=NN)cc1

nearest known ligand 0.80

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 20/20 0.80
▸ PRSS1 P07477 9/20 0.78
▸ PRSS2 P07478 3/20 0.70
▸ PRSS3 P35030 3/20 0.70
▸ F10 P00742 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6295968 0.93 F2 (0.69) F2PRSS1PRSS2PRSS3F10
SCHEMBL7379338 0.85 F2 (1.00) F2PRSS1PRSS2PRSS3F10
SCHEMBL6295975 0.80 F2 (0.52) F2PRSS1PRSS2PRSS3
SCHEMBL8366434 0.78 F2 (0.74) F2PRSS1PRSS2PRSS3F10
SCHEMBL4432108 0.78 F2 (0.77) F2PRSS1PRSS2PRSS3F10
Hydrochloric Acid SCHEMBL6436528 0.77 F2 (0.69) F2PRSS1PRSS2PRSS3
SCHEMBL5757596 0.76 F2 (0.69) F2PRSS1PRSS2PRSS3F10
SCHEMBL5851605 0.74 F2 (0.67) F2PRSS1PRSS2PRSS3F10
SCHEMBL14131528 0.74 F2 (0.67) F2PRSS1PRSS2PRSS3F10
SCHEMBL6287738 0.74 F2 (0.52) F2PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000032574-A1 NOVEL 2-PYRIDONE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE SANOFI-SYNTHELABO (FR) 2000-06-08 — — WO claimed
WO-2000032574-A1 NOVEL 2-PYRIDONE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE SANOFI-SYNTHELABO (FR) 2000-06-08 — — WO disclosed