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SCHEMBL7375841

SCHEMBL7375841

CSc1sc(C(=N)N)cc1N(S(=O)(=O)c1cccc(C)c1)S(=O)(=O)c1cccc(C)c1.CSc1sc(C(=N)N)cc1NS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ C1S P09871 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6927047 0.88 C1S (0.63) C1S
SCHEMBL6927266 0.86 C1S (0.63) C1S
SCHEMBL6926242 0.85 C1S (0.56) C1S
SCHEMBL6927428 0.83 C1S (0.54) C1S
SCHEMBL7382625 0.80 C1S (0.52) C1S
SCHEMBL7242120 0.80 C1S (0.65) C1S
SCHEMBL7997270 0.78 C1S (0.65) C1S
SCHEMBL7246975 0.77 C1S (0.53) C1S
SCHEMBL6925664 0.76 C1S (0.62) C1S
SCHEMBL7245020 0.76 C1S (0.50) C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1150979-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2001-11-07 — — EP claimed
WO-2000047578-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-08-17 — — WO claimed