⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12157434 | 1.00 | — | — | |
| SCHEMBL27305209 | 0.78 | — | — | |
| SCHEMBL9356800 | 0.72 | — | — | |
| SCHEMBL18878223 | 0.72 | — | — | |
| SCHEMBL12695687 | 0.72 | — | — | |
| SCHEMBL9797544 | 0.69 | — | — | |
| SCHEMBL14533553 | 0.69 | — | — | |
| SCHEMBL9797536 | 0.69 | — | — | |
| SCHEMBL24344739 | 0.69 | — | — | |
| SCHEMBL18199631 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230134859-A1 | METHOD FOR SCREENING FOR, METHOD FOR PRODUCING, AND METHOD FOR DESIGNING DRUG ACTIVE INGREDIENTS | SKY PHARMA CO., LTD. (JP) | 2023-05-04 | — | — | US | disclosed |
| US-20170232113-A1 | QUATERNARY AMINE COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2017-08-17 | — | — | US | disclosed |
| US-20170232113-A1 | QUATERNARY AMINE COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2017-08-17 | — | — | US | disclosed |
| US-20160346440-A1 | TROPOELASTIN FOR PROMOTING ENDOTHELIAL CELL ADHESION OR MIGRATION | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2016-12-01 | — | — | US | disclosed |
| US-9481676-B2 | Azepino[4,5-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-11-01 | — | — | US | disclosed |
| US-20160310611-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH INC. (US) | 2016-10-27 | — | — | US | disclosed |
| US-20160279260-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2016-09-29 | — | — | US | disclosed |
| US-20160279261-A1 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2016-09-29 | — | — | US | disclosed |
| US-9409910-B2 | Azepino[4,5-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-9381282-B2 | Tropoelastin for promoting endothelial cell adhesion or migration | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-07-05 | — | — | US | disclosed |
| US-7612038-B2 | Stabilizing dystrophin associated protein complexes; abnormal synapses or neuromuscular junction disorders | BROWN UNIVERSITY (US) | 2009-11-03 | — | — | US | disclosed |
| US-7524811-B2 | Anti-angiogenic peptides from the N-terminus of endostatin | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-04-28 | — | — | US | disclosed |
| US-20080241099-A1 | Inhibitors of MBP 85-99 or proteolipid protein (PLP) 40-60-specific HLA-DR-2-restricted T cell clones; multiple sclerosis; rheumatoid arthritis; solid phase synthesis; kits | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-10-02 | — | — | US | disclosed |
| US-20080194462-A1 | Methods and Compositions for Treatment of Autoimmune Diseases | PEPTIMMUNE, INC. (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080194462-A1 | Methods and Compositions for Treatment of Autoimmune Diseases | PEPTIMMUNE, INC. (US) | 2008-08-14 | — | — | US | disclosed |
| US-7381790-B2 | For therapy of multiple sclerosis (MS) in humans | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-06-03 | — | — | US | disclosed |
| US-20080050361-A1 | STAPHYLOCOCCUS AUREAS SPECIFIC ANTI-INFECTIVES | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2008-02-28 | — | — | US | disclosed |
| US-20070292873-A1 | Bacterial iron acquisition targets | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2007-12-20 | — | — | US | disclosed |
| US-7235244-B2 | Compositions and methods for treating papillomavirus-infected cells | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-06-26 | — | — | US | disclosed |
| US-20070129440-A1 | Polypharmacophoric agents | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2007-06-07 | — | — | US | disclosed |