Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1914726 | 0.86 | RECQL (0.46) | RECQLMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL1914722 | 0.86 | RECQL (0.46) | RECQLMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL7431926 | 0.84 | RECQL (0.53) | RECQLMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL7377043 | 0.84 | RECQL (0.53) | RECQLMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL7377051 | 0.84 | RECQL (0.53) | RECQLMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL1915838 | 0.79 | RECQL (0.69) | RECQLMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL1915834 | 0.79 | RECQL (0.69) | RECQLMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL1915837 | 0.79 | RECQL (0.69) | RECQLMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL2875911 | 0.78 | RECQL (0.42) | RECQLALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11818250 | 0.76 | RECQL (0.51) | RECQLTDP1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912545-A1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997026257-A1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1997-07-24 | — | — | WO | disclosed |