Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 8/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770073 | 0.81 | BACE1 (0.56) | ANPEPBACE1MAP2K2MAP2K1LMNA | |
| SCHEMBL28251159 | 0.81 | ANPEP (0.53) | ANPEPBACE1CYP2A6MAP2K2MAP2K1 | |
| SCHEMBL29738643 | 0.81 | BACE1 (0.56) | ANPEPBACE1MAP2K2MAP2K1LMNA | |
| SCHEMBL30418057 | 0.79 | BACE1 (0.55) | ANPEPBACE1CYP2A6LMNASTAT3 | |
| SCHEMBL453379 | 0.77 | ANPEP (0.50) | ANPEPBACE1CYP2A6MAP2K2MAP2K1 | |
| SCHEMBL5282055 | 0.77 | CYP2A6 (0.50) | ANPEPBACE1CYP2A6MAP2K2MAP2K1 | |
| SCHEMBL6493935 | 0.77 | CYP2A6 (0.50) | ANPEPBACE1CYP2A6MAP2K2MAP2K1 | |
| SCHEMBL10914762 | 0.77 | AGXT (0.44) | CYP2A6LMNASMN1; SMN2 | |
| SCHEMBL30417509 | 0.77 | CNR2 (0.56) | ANPEPBACE1CYP2A6LMNACNR2 | |
| SCHEMBL30418036 | 0.77 | CNR2 (0.56) | ANPEPBACE1CYP2A6LMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071751-C | Reversible protease inhibitors | ARRIS PHARM CORP (US) | 2001-09-26 | — | — | CN | disclosed |
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| CN-1184472-A | Reversible protease inhibitors | ARRIS PHARM CORP (US) | 1998-06-10 | — | — | CN | disclosed |
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |
| EP-0712404-A1 | NOVEL BENZOTHIOPHENE ANALOGS AS ANTIVIRAL AGENTS | STANFORD RES INST INT (US) | 1996-05-22 | — | — | EP | disclosed |