SCHEMBL7376904

SCHEMBL7376904

Nc1nccc(NCCN2CC[C@H](NS(=O)(=O)C=Cc3ccc(Cl)s3)C2=O)c1Cl

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7377206 0.93 F10 (0.49) F10
SCHEMBL7537562 0.83 F10 (0.56) F10
SCHEMBL1651452 0.78 F10 (0.49) F10
SCHEMBL1651454 0.78 F10 (0.49) F10
SCHEMBL7378866 0.77 F10 (0.59) F10
SCHEMBL6223826 0.74 F10 (0.50) F10
SCHEMBL6220812 0.73 F10 (0.51) F10
SCHEMBL7538090 0.73 F10 (0.51) F10
SCHEMBL7545908 0.72 F10 (0.51) F10
Trifluoroacetic Acid SCHEMBL7375929 0.70 F10 (0.56) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP disclosed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed