Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607064 | 0.85 | MME (0.48) | L3MBTL1CTSL | |
| SCHEMBL7607068 | 0.85 | MME (0.48) | L3MBTL1CTSL | |
| SCHEMBL27880853 | 0.79 | ATM (0.60) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL8487195 | 0.78 | ATM (0.53) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL3725043 | 0.76 | ATM (0.63) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL8724389 | 0.76 | ATM (0.63) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL12666720 | 0.76 | ATM (0.63) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL6302437 | 0.76 | ATM (0.63) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL2602049 | 0.76 | ATM (0.63) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL2734812 | 0.76 | ATM (0.63) | ATMALDH1A1CYP2C9CYP2C19THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049662-A1 | INHIBITORS OF ALPHA4 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999036393-A1 | INHIBITORS OF α4 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 1999-07-22 | — | — | WO | disclosed |