Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 14/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 14/20 | 0.69 |
| ▸ | PDE4A | P27815 | 13/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.69 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267795 | 0.82 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10386700 | 0.81 | PDE3B (0.73) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7431842 | 0.80 | PDE3B (0.75) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7383314 | 0.80 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7428378 | 0.80 | PDE3B (0.78) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7432713 | 0.78 | PDE4A (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7429101 | 0.78 | PDE3B (0.71) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7427262 | 0.77 | PDE4A (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7427801 | 0.77 | PDE3B (1.00) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7373436 | 0.76 | PDE3B (0.68) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381374-A1 | Phosphodiesterase inhibitors | LES LABORATOIRES BEECHAM S.A. (FR) | 1990-08-08 | — | — | EP | disclosed |