Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378630 | 1.00 | AVPR2 (0.41) | AVPR2ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7370821 | 0.91 | GAA (0.39) | AVPR2ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7370827 | 0.91 | GAA (0.39) | AVPR2ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7372350 | 0.86 | AVPR2 (0.43) | AVPR2ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7376626 | 0.85 | AVPR2 (0.41) | AVPR2 | |
| SCHEMBL7374760 | 0.85 | AVPR2 (0.43) | AVPR2ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7378632 | 0.85 | AVPR2 (0.41) | AVPR2ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7376574 | 0.84 | AVPR2 (0.42) | AVPR2ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7376764 | 0.83 | PPARG (0.42) | AVPR2ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7373910 | 0.81 | AVPR2 (0.41) | AVPR2ALDH1A1GAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |