Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378649 | 1.00 | MEN1 (0.54) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7434412 | 1.00 | MEN1 (0.54) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7434406 | 1.00 | MEN1 (0.54) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7378646 | 1.00 | MEN1 (0.54) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7434401 | 1.00 | MEN1 (0.54) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7431914 | 0.90 | MAPT (0.51) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7431928 | 0.90 | MAPT (0.51) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7438224 | 0.90 | MAPT (0.55) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7431922 | 0.90 | MAPT (0.51) | MEN1POLBKMT2AMAPTHPGD | |
| SCHEMBL7438218 | 0.90 | MAPT (0.55) | MEN1POLBKMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889879-B1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6248743-B1 | ANTITHROMBOTIC AGENTS EFFECTIVE TO INHIBIT THE PRODUCTION OF TYPE 1 PLASMINOGEN ACTIVATOR INHIBITOR (PAI-1) | TANABE SEIYAKU CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0889879-A1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997036864-A1 | BUTADIENE DERIVATIVES AND PROCESS FOR PREPARING THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1997-10-09 | — | — | WO | disclosed |
| EP-0563798-B1 | Butadiene derivatives, their preparation and use as an antithrombotic agent | TANABE SEIYAKU CO (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5514815-A | ANTITHROMBOTIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0563798-A1 | Butadiene derivatives, their preparation and use as an antithrombotic agent | TANABE SEIYAKU CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |