Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7378773

COc1ccc2ccc(S(=O)(=O)N(C)[C@H]3CCN(Cc4ccc5ccc(N)nc5c4)C3=O)cc2c1.O=C(O)C(F)(F)F

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 14/20 0.62
F2 P00734 11/20 0.62
PLG P00747 1/20 0.59
PLAT P00750 1/20 0.59
PROC P04070 1/20 0.59
KLK6 Q92876 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7382209 0.89 F10 (0.61) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7538458 0.87 F10 (0.59) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7219682 0.87 F10 (0.64) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7215947 0.87 F10 (0.64) F10F2PLGPLATPROC
SCHEMBL7550978 0.86 F10 (0.68) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7384749 0.85 F10 (0.66) F10F2PLGPROC
Trifluoroacetic Acid SCHEMBL2329444 0.84 F10 (0.68) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL2329447 0.84 F10 (0.68) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL7538032 0.84 F10 (0.52) F10F2PLGPROCKLK6
Trifluoroacetic Acid SCHEMBL2328333 0.82 F10 (0.89) F10F2PLGPLATPROC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944386-B1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMA INC (US) 2002-09-18 EP claimed
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP disclosed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed