Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370518 | 0.90 | F2 (0.53) | F2TSHRLMNAHTTGAA | |
| SCHEMBL8664965 | 0.83 | F2 (0.62) | F2TSHR | |
| SCHEMBL8647376 | 0.80 | TSHR (0.41) | F2TSHRLMNAHTTGAA | |
| SCHEMBL8649759 | 0.76 | F2 (0.54) | F2MCL1 | |
| SCHEMBL8652523 | 0.76 | F2 (0.54) | F2 | |
| SCHEMBL7374410 | 0.75 | F2 (0.53) | F2 | |
| SCHEMBL7360906 | 0.74 | F2 (0.47) | F2TSHR | |
| SCHEMBL7409794 | 0.73 | F2 (0.63) | F2LMNAHTTGAA | |
| SCHEMBL8543009 | 0.72 | F2 (0.79) | F2 | |
| SCHEMBL7378503 | 0.72 | F2 (0.53) | F2TSHRLMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795892-A | ANTICOAGULANTS | BOEHRINGER MANNEIM GMBH (DE) | 1998-08-18 | — | — | US | disclosed |
| EP-0778829-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006832-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-03-07 | — | — | WO | disclosed |