Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639421 | 0.82 | F2 (0.53) | F2PRSS2 | |
| SCHEMBL3642375 | 0.81 | F2 (0.55) | F2PRSS2 | |
| SCHEMBL4642756 | 0.81 | TDP1 (0.55) | F2ALPLTDP1GAAMAPK1 | |
| SCHEMBL14878116 | 0.81 | F2 (0.55) | F2PRSS2 | |
| SCHEMBL7444372 | 0.81 | F2 (0.53) | F2 | |
| SCHEMBL3642393 | 0.80 | F2 (0.54) | F2PRSS2 | |
| SCHEMBL7377227 | 0.80 | F2 (0.54) | F2PRSS2 | |
| SCHEMBL7332517 | 0.80 | F2 (0.54) | F2PRSS2 | |
| SCHEMBL8160877 | 0.80 | F2 (0.54) | F2PRSS2 | |
| SCHEMBL5866160 | 0.78 | F2 (0.55) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795892-A | ANTICOAGULANTS | BOEHRINGER MANNEIM GMBH (DE) | 1998-08-18 | — | — | US | disclosed |
| EP-0778829-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006832-A1 | NOVEL 4-AMINOPYRIDAZINES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-03-07 | — | — | WO | disclosed |