Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.64 |
| ▸ | NAMPT | P43490 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380393 | 0.85 | PTPN2 (0.68) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| Acetic Acid SCHEMBL8143914 | 0.85 | PTPN2 (0.65) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| SCHEMBL7374084 | 0.84 | PTPN2 (0.64) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| SCHEMBL7372038 | 0.84 | PTPN2 (0.67) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| Acetic Acid SCHEMBL7374080 | 0.84 | PTPN2 (0.60) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| SCHEMBL8144011 | 0.83 | PTPN2 (0.62) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| SCHEMBL7375251 | 0.82 | PTPN2 (0.61) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| SCHEMBL4518131 | 0.81 | PTPN2 (0.62) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| SCHEMBL29037711 | 0.81 | NAMPT (0.69) | PTPN2PTPN1PTPN6NAMPTMAPT | |
| SCHEMBL3256196 | 0.81 | NAMPT (0.69) | PTPN2PTPN1PTPN6NAMPTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069143-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-30 | — | — | US | disclosed |
| EP-0885213-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0885213-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997025323-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-17 | — | — | WO | disclosed |