Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.44 |
| ▸ | REN | P00797 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735809 | 0.95 | ACE (0.49) | ACERENRAB9AKDM4EF2 | |
| SCHEMBL22021311 | 0.95 | ACE (0.49) | ACERENRAB9AKDM4EF2 | |
| SCHEMBL16681841 | 0.95 | ACE (0.49) | ACERENRAB9AKDM4EF2 | |
| SCHEMBL26121576 | 0.88 | BLM (0.41) | ACERENRAB9ASMN1; SMN2SLC6A1 | |
| SCHEMBL13312887 | 0.87 | CNR1 (0.40) | ACERENRAB9ASMN1; SMN2SLC6A1 | |
| SCHEMBL7388386 | 0.86 | ACE (0.41) | ACERENRAB9ASMN1; SMN2SLC6A1 | |
| SCHEMBL8197078 | 0.84 | ACE (0.46) | ACERENRAB9AKDM4EF2 | |
| SCHEMBL26123425 | 0.83 | ACE (0.43) | ACERENRAB9AKDM4EF2 | |
| SCHEMBL3711047 | 0.83 | CNR1 (0.47) | ACERENRAB9ASMN1; SMN2SLC6A1 | |
| SCHEMBL3711045 | 0.83 | CNR1 (0.47) | ACERENRAB9ASMN1; SMN2SLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251919-B1 | ADMINISTERING ANILINE DERIVATIVE FOR THERAPY OF PAIN | WARNER-LAMBERT | 2001-06-26 | — | — | US | disclosed |
| WO-1999043658-A1 | HETEROCYCLIC SUBSTITUTED ANILINE CALCIUM CHANNEL BLOCKERS | WARNER-LAMBERT COMPANY (US) | 1999-09-02 | — | — | WO | disclosed |