SCHEMBL7380435

SCHEMBL7380435

Bc1ccccc1S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MYC P01106 1/20 0.44
TTR P02766 2/20 0.42
FABP4 P15090 1/20 0.38
CCNA2 P20248 1/20 0.38
CDK2 P24941 1/20 0.38
MAPK14 Q16539 1/20 0.38
NR4A1 P22736 1/20 0.37
PGAM1 P18669 1/20 0.36
CYP1A2 P05177 1/20 0.36
GAA P10253 2/20 0.36
CHAT P28329 1/20 0.35
SNCA P37840 1/20 0.35
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA12 O43570 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150335 0.81 TSHR (0.55) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL29664068 0.81 TSHR (0.55) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL8607533 0.78 TSHR (0.52) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL2972939 0.78 TSHR (0.52) TSHRSMN1; SMN2MYCTTRFABP4
Hydrochloric Acid SCHEMBL627715 0.78 TSHR (0.52) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL6678754 0.78 TSHR (0.52) TSHRSMN1; SMN2MYCTTRFABP4
Potassium SCHEMBL999033 0.78 TSHR (0.52) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL10627282 0.78 MYC (0.56) TSHRSMN1; SMN2MYCTTRFABP4
SCHEMBL6552111 0.78 TSHR (0.52) TSHRSMN1; SMN2MYCTTRFABP4
Potassium SCHEMBL6749446 0.78 TSHR (0.52) TSHRSMN1; SMN2MYCTTRFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165472-A4 METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL MYERS SQUIBB CO (US) 2002-11-20 EP disclosed
EP-1165472-A1 METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL-MYERS SQUIBB COMPANY (US) 2002-01-02 EP disclosed
US-6313308-B1 CONTACTING BORONIC ACID-SUBSTITUTED BENZENESULFONIC ACID WITH HALOBENZENE IN PRESENCE OF PALLADIUM CATALYST AND ALKALI METAL COMPOUND BASE; SALT FORMATION, CHLORINATION, COUPLING BRISTOL-MYERS SQUIBB COMPANY 2001-11-06 US disclosed
WO-2000056685-A1 METHODS FOR THE PREPARATION OF BIPHENYL ISOXAZOLE SULFONAMIDES BRISTOL-MYERS SQUIBB COMPANY (US) 2000-09-28 WO disclosed