Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.65 |
| ▸ | CNR1 | P21554 | 4/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739583 | 0.79 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL737821 | 0.79 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL737883 | 0.78 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL737757 | 0.78 | CNR2 (0.80) | CNR2CNR1 | |
| SCHEMBL4122540 | 0.77 | CNR2 (0.64) | CNR2CNR1TMEM97SIGMAR1 | |
| SCHEMBL737679 | 0.76 | CNR2 (0.81) | CNR2CNR1TMEM97SIGMAR1HTR3A | |
| SCHEMBL738108 | 0.75 | CNR2 (0.71) | CNR2CNR1TMEM97SIGMAR1 | |
| SCHEMBL13588573 | 0.75 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL736660 | 0.75 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL738882 | 0.74 | CNR2 (0.71) | CNR2CNR1TMEM97SIGMAR1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138177-B2 | Benzimidazolone derivatives as CB2 receptor ligands | PFIZER INC. (US) | 2012-03-20 | — | — | US | claimed |