Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3518971 | 1.00 | TACR1 (0.88) | TACR1 | |
| SCHEMBL3513722 | 0.94 | TACR1 (0.89) | TACR1 | |
| SCHEMBL7389885 | 0.94 | TACR1 (0.89) | TACR1 | |
| SCHEMBL3517349 | 0.94 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7381227 | 0.94 | TACR1 (1.00) | TACR1 | |
| SCHEMBL3516200 | 0.93 | TACR1 (0.86) | TACR1 | |
| SCHEMBL7386236 | 0.93 | TACR1 (0.86) | TACR1 | |
| SCHEMBL3514375 | 0.92 | TACR1 (0.96) | TACR1 | |
| SCHEMBL9222449 | 0.92 | TACR1 (0.96) | TACR1 | |
| SCHEMBL3515836 | 0.92 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995000498-A1 | N,N-DIACYLPIPERAZINES | MERCK & CO., INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| US-5348955-A | Angiotensis II antagonists | MERCK & CO., INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5292726-A | N,N-diacylpiperazines | MERCK & CO., INC. (US) | 1994-03-08 | — | — | US | disclosed |
| WO-1992020661-A1 | N, N-DIACYLPIPERAZINES | MERCK & CO., INC. (US) | 1992-11-26 | — | — | WO | disclosed |