SCHEMBL73859

SCHEMBL73859

[CH2]c1nnn[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL238233 0.62
SCHEMBL8424100 0.62
SCHEMBL5838655 0.62
SCHEMBL308487 0.61
SCHEMBL11873862 0.60
SCHEMBL4870821 0.60
SCHEMBL278437 0.60
SCHEMBL298032 0.59
SCHEMBL1239469 0.58
SCHEMBL19387727 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2401 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4373835-A1 MACROCYLIC IMMUNOMODULATORS Bristol-Myers Squibb Company (US) 2024-05-29 EP claimed
WO-2024104425-A1 KRAS INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF 广东东阳光药业股份有限公司 2024-05-23 WO claimed
CN-118047801-A KRAS inhibitor compound, pharmaceutical composition and application thereof 广东东阳光药业股份有限公司 2024-05-17 CN claimed
CN-117940445-A Macrocyclic immunomodulators 百时美施贵宝公司 2024-04-26 CN claimed
EP-3596059-B1 HETEROCYCLIC COMPOUNDS USEFUL AS DUAL ATX/CA INHIBITORS HOFFMANN LA ROCHE (CH) 2024-04-24 EP claimed
CN-111683950-B AhR modulators 伊迪亚生物科学有限公司 2024-04-16 CN claimed
WO-2024022481-A1 PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF 苏中药业集团股份有限公司 2024-02-01 WO claimed
CN-117062815-A VMAT2 inhibitors and methods of use 纽罗克里生物科学有限公司 2023-11-14 CN claimed
US-11767323-B2 Tricyclic pyridone compounds as JAK2 V617F inhibitors INCYTE CORPORATION (US) 2023-09-26 US claimed
EP-4219495-A1 AHR MODULATORS Ideaya Biosciences, Inc. (US) 2023-08-02 EP claimed
US-4335240-A Process for cyclization ELI LILLY AND COMPANY (US) 1982-06-15 US claimed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US claimed
US-4302391-A Unsymmetrical azetidinone aldehyde disulfides and process ELI LILLY AND COMPANY (US) 1981-11-24 US claimed
US-4297488-A 7-α-Methoxy cephalosporins MERCK & CO., INC. (US) 1981-10-27 US claimed
US-4293493-A Azetidinone alcohol disulfides and process for cyclization ELI LILLY AND COMPANY (US) 1981-10-06 US claimed
US-4293495-A Symmetrical azetidinone aldehyde disulfides and process ELI LILLY AND COMPANY (US) 1981-10-06 US claimed
US-4258040-A Cephalosporin compounds MERCK & CO., INC. (US) 1981-03-24 US claimed
US-4206211-A BACTERICIDES FARMITALIA CARLO ERBA S.P.A. (IT) 1980-06-03 US claimed
US-4171304-A 2-Iodomethylpenams CONNLAB HOLDINGS LIMITED (CA) 1979-10-16 US claimed
US-4060687-A Cephalosporins having a 3-α substituted alkyl grouping MERCK & CO., INC. (US) 1977-11-29 US claimed