Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834516 | 0.81 | HPGD (0.54) | DDB1CRBNALDH1A1KDM4ECYP1A2 | |
| SCHEMBL15284716 | 0.80 | CYP2A6 (0.49) | ALDH1A1HSD17B10MAPTGAAL3MBTL1 | |
| SCHEMBL4738844 | 0.76 | GAA (0.60) | ALDH1A1KDM4EHPGDNPC1MAPT | |
| SCHEMBL13934651 | 0.76 | DDB1 (0.50) | DDB1CRBNALDH1A1KDM4ECYP1A2 | |
| SCHEMBL4785233 | 0.74 | CA12 (0.69) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL14446904 | 0.74 | MYC (0.50) | ALDH1A1KDM4EGAAL3MBTL1KMT2A | |
| SCHEMBL17636764 | 0.73 | DDB1 (0.52) | DDB1CRBNALDH1A1KDM4ECYP1A2 | |
| SCHEMBL28509979 | 0.73 | DDB1 (0.52) | DDB1CRBNALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14280868 | 0.73 | DDB1 (0.47) | DDB1CRBNALDH1A1KDM4ECYP1A2 | |
| SCHEMBL14446905 | 0.73 | SMN1; SMN2 (0.54) | CRBNALDH1A1KDM4EHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032569-A1 | IMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-SYNTHELABO (FR) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999025710-A1 | IMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | SANOFI-SYNTHELABO (FR) | 1999-05-27 | — | — | WO | disclosed |