Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6775860 | 1.00 | HPGD (0.43) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL13349281 | 1.00 | HPGD (0.43) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7387263 | 1.00 | HPGD (0.43) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL855309 | 1.00 | HPGD (0.43) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8197412 | 1.00 | HPGD (0.43) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL22413339 | 0.90 | NR1H2 (0.49) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2251815 | 0.90 | NR1H2 (0.49) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL22413340 | 0.90 | NR1H2 (0.49) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL2251816 | 0.90 | NR1H2 (0.49) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12356485 | 0.89 | HPGD (0.43) | HPGDALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |