Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.31 |
| ▸ | LONP1 | P36776 | 2/20 | 0.31 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.31 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.31 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.31 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9002986 | 0.98 | F2 (0.32) | F2DRD2HTR2ANAMPTPSMB5 | |
| SCHEMBL7391767 | 0.93 | F2 (0.33) | F2LMNAHPGD | |
| SCHEMBL9211874 | 0.93 | F2 (0.38) | F2PSMB5PSMB8LMNAHPGD | |
| Hydrochloric Acid SCHEMBL9002841 | 0.93 | F2 (0.33) | F2LMNAHPGD | |
| SCHEMBL7396755 | 0.91 | F2 (0.32) | F2PSMB5LONP1PSMB11PSMA7 | |
| Hydrochloric Acid SCHEMBL9002946 | 0.91 | F2 (0.33) | F2PSMB5LONP1PSMB11PSMA7 | |
| SCHEMBL9002975 | 0.90 | PSMB5 (0.33) | F2PSMB5LONP1PSMB11PSMA7 | |
| SCHEMBL7387444 | 0.89 | F2 (0.40) | F2 | |
| Hydrochloric Acid SCHEMBL9002905 | 0.89 | F2 (0.33) | F2PSMB5LONP1PSMB11PSMA7 | |
| SCHEMBL7395162 | 0.89 | PSMB5 (0.33) | F2PSMB5LONP1PSMB11PSMA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559232-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0641779-A1 | Novel 1-amidinopiperdines and 4-amidinomorpholines as aggregation inhibitions | F. HOFFMANN-LA ROCHE AG (CH) | 1995-03-08 | — | — | EP | disclosed |