Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492401 | 0.83 | MAPT (0.58) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10777470 | 0.83 | MAPT (0.58) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10777521 | 0.78 | MEN1 (0.57) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10782017 | 0.78 | CACNA1F (0.65) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10782134 | 0.77 | MEN1 (0.61) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4637034 | 0.76 | CYP1A2 (0.50) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10873574 | 0.74 | MAPT (0.56) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10781991 | 0.74 | MAPT (0.56) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11000189 | 0.74 | MAPT (0.56) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10992458 | 0.74 | CACNA1F (0.54) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254570-A | Acyl derivative of dianhydrohexitols | PFIZER INC. (US) | 1993-10-19 | — | — | US | claimed |